Article
Identification of novel transcript variants of estrogen receptor α, β and progesterone receptor gene in human endometrium.
Endocrine - 1 Jun 2010
Springwald Anette, Lattrich Claus, Skrzypczak Maciek, Goerse Regina, Ortmann Olaf, Treeck Oliver
Abstract excerpt
The human progesterone receptor (PR) and estrogen receptor genes (ESR1 and ESR2) are known to code for a multitude of transcript variants resulting from alternative splicing. Many of them are translated into nuclear receptor proteins with altered structure and function. Expression of these alternative estrogen and progesterone receptors modulates the cellular response to sexual steroid hormones. Recent studies...
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