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Article

Altered expression of exon 6 deleted progesterone receptor variant mRNA between normal human breast and breast tumour tissues.

British journal of cancer - 1 May 1999

Leygue E, Dotzlaw H, Watson P H, Murphy L C

Abstract excerpt

The progesterone receptor (PR) is an important prognostic marker in breast cancer as well as a marker of responsiveness to endocrine therapies. The presence of several exon-deleted PR variant mRNAs in both normal and neoplastic breast samples has recently been reported. Amongst them, a variant mRNA deleted in exon 6 (D6-PR mRNA) that if translated would encode a truncated PR-like protein missing the hormone...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10408841
DOI: 10.1038/sj.bjc.6690366
PMCID: PMC2362307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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