Article
Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 2011
Oikonen Mervi, Tikkanen Emmi, Juhola Jonna, Tuovinen Tarja, Seppälä Ilkka, Juonala Markus, Taittonen Leena, Mikkilä Vera, Kähönen Mika, Ripatti Samuli, Viikari Jorma, Lehtimäki Terho, Havulinna Aki S, Kee Frank, Newton-Cheh Christopher, Peltonen Leena, Schork Nicholas J, Murray Sarah S, Berenson Gerald S, Chen Wei, Srinivasan Sathanur R, Salomaa Veikko, Raitakari Olli T
Abstract excerpt
Clinical relevance of a genetic predisposition to elevated blood pressure was quantified during the transition from childhood to adulthood in a population-based Finnish cohort (N=2357). Blood pressure was measured at baseline in 1980 (age 3-18 years) and in follow-ups in 1983, 1986, 2001, and 2007. Thirteen single nucleotide polymorphisms associated with blood pressure were genotyped, and 3 genetic risk scores...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.