Article
Frequency of three common mutations of CARD15/NOD2 gene in Iranian IBD patients.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 1 Jan 2000
Derakhshan Faramarz, Naderi Nosratollah, Farnood Alma, Firouzi Farzad, Habibi Manijeh, Rezvany Mohammad Reza, Javeri Arash, Bahari Ali, Balaii Hedieh, Rad Mahta Ghaffarzadeh, Aghazadeh Rahim, Zali Mohammad Reza
Abstract excerpt
BACKGROUND: The CARD15/NOD2 gene, located on the pericentromeric region of chromosome 16 (IBD1) has been reported to have an association with IBD, especially Crohn's disease. Three common mutations of CARD15 are variably associated with Crohn's disease in different ethnic groups. We evaluated the frequency of these mutations (R702W, G908R and 1007fsinsC) in Iranian IBD patients and compared it with the healthy...
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