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Article

Crystallization and preliminary X-ray structural studies of human prouroguanylin.

Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Jun 2008

Ito Len, Hidaka Yuji, Okumura Masaki, Konishi Hironori, Adermann Knut, Yamaguchi Hiroshi

Abstract excerpt

Uroguanylin, which serves as an endogenous ligand of guanylyl cyclase C, is initially secreted in the form of a precursor, prouroguanylin. The N-terminal region of prouroguanylin interacts with the mature portion of prouroguanylin during the folding pathway. Here, a preliminary X-ray crystallographic study of prouroguanylin is presented. Prouroguanylin was refolded, purified and crystallized using the...

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Identifiers

PMID: 18540068
DOI: 10.1107/S1744309108013444
PMCID: PMC2496868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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