Article
Genome-wide linkage analysis of heroin dependence in Han Chinese: results from Wave Two of a multi-stage study.
Drug and alcohol dependence - 1 Nov 2008
Glatt Stephen J, Lasky-Su Jessica A, Zhu Shao C, Zhang Ruimin, Zhang Bo, Li Jixiang, Yuan Xiaobo, Li Jianhua, Lyons Michael J, Faraone Stephen V, Tsuang Ming T
Abstract excerpt
Previously we reported the results of Wave One of a genome-wide search for heroin dependence susceptibility loci in Han Chinese families from Yunnan Province, China, near Asia's "Golden Triangle". Our initial analysis of 194 independent affected sibling-pairs from 192 families identified two regions with nonparametric linkage (NPL) Z-scores greater than 2.0, which were suggestive of linkage. Presently we have...
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