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Article

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing.

Proceedings of the National Academy of Sciences of the United States of America - 10 Jun 2008

Azuma-Mukai Asuka, Oguri Hideo, Mituyama Toutai, Qian Zhi Rong, Asai Kiyoshi, Siomi Haruhiko, Siomi Mikiko C

Abstract excerpt

Small RNAs triggering RNA silencing are loaded onto Argonautes and then sequence-specifically guide them to target transcripts. Epitope-tagged human Argonautes (hAgo1, hAgo2, hAgo3, and hAgo4) are associated with siRNAs and miRNAs, but only epitope-tagged hAgo2 has been shown to have Slicer activ...

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Identifiers

PMID: 18524951
DOI: 10.1073/pnas.0800334105
PMCID: PMC2430345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18524951-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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