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Article

Butyrate inhibits functional differentiation of human monocyte-derived dendritic cells.

Cellular immunology - 1 Jan 2000

Wang Biao, Morinobu Akio, Horiuchi Marika, Liu Jun, Kumagai Shunichi

Abstract excerpt

Dendritic cells (DCs) play a key role in immune function through antigen presentation by MHC and CD1, as well as cytokine production that shapes the immune response. Here we report that butyrate, a histone deacetylase inhibitor, inhibits the functional differentiation of human monocyte-derived DCs. Mature DCs were generated from monocytes in the presence of granulocyte macrophage colony-stimulating factor...

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Identifiers

PMID: 18522857
DOI: 10.1016/j.cellimm.2008.04.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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