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Article

Dexamethasone inhibits maturation and alters function of monocyte-derived dendritic cells from cord blood.

Pediatric research - 1 Jul 2005

Mainali Elsie S, Kikuchi Takeshi, Tew John G

Abstract excerpt

Critically ill infants are treated with dexamethasone (Dx) and other glucocorticoids to reduce inflammation and to promote lung and cardiac function. The neonatal immune system is immature, so neonatal dendritic cells (DCs) might be especially sensitive to glucocorticoid-mediated immunosuppression. To test this, we compared Dx treatment of monocyte-derived DCs from cord (CB) and adult blood (AB). Dx decreased...

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Identifiers

PMID: 15774840
DOI: 10.1203/01.PDR.0000157677.72136.09

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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