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Article

Polymorphisms in ABCG5/G8 transporters linked to hypercholesterolemia and gallstone disease.

Nutrition reviews - 1 Jun 2008

Rudkowska Iwona, Jones Peter J H

Abstract excerpt

ATP-binding cassette (ABC) transporters function in the homeostasis of lipids. Dysfunction of ABC transporters is frequently associated with disease. This review examines links between polymorphisms of ABC G5 (ABCG5) and G8 (ABCG8) transporter genes to hypercholesterolemia and to gallstone disease risk. Various polymorphisms (A632V, T400K, D19H, M429V, and C54Y) in the ABCG8 and ABCG5 (Q604E) gene have been found...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 5
Share to ATP Binding Cassette Transporter, Subfamily G, Member 8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18522623
DOI: 10.1111/j.1753-4887.2008.00042.x

Genes

ABCG5
ABCG8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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