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Article

Single nucleotide polymorphism in the ABCG8 transporter gene is associated with gallbladder cancer susceptibility.

Liver international : official journal of the International Association for the Study of the Liver - 1 Jul 2009

Srivastava Anvesha, Tulsyan Sonam, Pandey Sachchida Nand, Choudhuri Gourdas, Mittal Balraj

Abstract excerpt

BACKGROUND: Gallbladder cancer (GBC) usually arises against the background of gallstone disease, which may be causatively related to supersaturation of cholesterol in bile. An imbalance in cholesterol homeostasis because of oversecretion of cholesterol in the gallbladder promotes gallstone formation. The excretion of cholesterol from the liver is regulated by adenosine triphosphate-binding cassette transporter...

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Topics

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 8
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol

Share to Gallbladder Neoplasms

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Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 19018975
DOI: 10.1111/j.1478-3231.2008.01907.x

Genes

ABCG8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Single nucleotide polymorphism in the ABCG8 transporter gene is associated with gallbladder cancer susceptibility.PMID 19018975Read ↗

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Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease.Semantic proximity Read ↗

Correlation of serum biochemical characteristics and ABCG8 genetic variant (rs 11887534) with gall stone compositions and risk of gallstone disease in Egyptian patients.Semantic proximity Read ↗

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