Single nucleotide polymorphisms and haplotypes in the gene for vascular endothelial growth factor and risk of prostate cancer.

doi:10.1016/j.ejca.2008.04.021

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Article

Single nucleotide polymorphisms and haplotypes in the gene for vascular endothelial growth factor and risk of prostate cancer.

European journal of cancer (Oxford, England : 1990) - 1 Jul 2008

Langsenlehner Tanja, Langsenlehner Uwe, Renner Wilfried, Krippl Peter, Mayer Ramona, Wascher Thomas C, Kapp Karin S

Abstract excerpt

Vascular endothelial growth factor (VEGF) plays a key role in the regulation of angiogenesis and has been related to cancer development and progression. To evaluate the role of VEGF single nucleotide polymorphisms (SNPs) and haplotypes in prostate cancer, we performed a case-control study including 702 prostate cancer patients and 702 male age-matched healthy control subjects. Seven VEGF candidate polymorphisms...

Topics

Aged
Haplotypes
Humans
Linkage Disequilibrium
Male
Polymorphism, Single Nucleotide
Prostatic Neoplasms
Risk Factors
Vascular Endothelial Growth Factor A

Source

Open in PubMed

Identifiers

PMID: 18514506
DOI: 10.1016/j.ejca.2008.04.021

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