Article
Genetic polymorphisms in the vascular endothelial growth factor gene and breast cancer risk. The Austrian "tumor of breast tissue: incidence, genetics, and environmental risk factors" study.
Breast cancer research and treatment - 1 May 2008
Langsenlehner Uwe, Wolf Gerald, Langsenlehner Tanja, Gerger Armin, Hofmann Günter, Clar Heimo, Wascher Thomas C, Paulweber Bernhard, Samonigg Hellmut, Krippl Peter, Renner Wilfried
Abstract excerpt
PURPOSE: Vascular endothelial growth factor (VEGF) is a key regulator of tumor-induced angiogenesis and is required for growth of tumors. We tested the hypothesis that VEGF gene polymorphisms may be associated with breast cancer. EXPERIMENTAL DESIGN: We performed a case-control study including 804 female incident breast cancer patients and 804 female age-matched healthy control subjects. We selected seven VEGF...
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