Article
Genetic polymorphisms in the vascular endothelial growth factor gene and breast cancer risk. The Austrian "tumor of breast tissue: incidence, genetics, and environmental risk factors" study.
Breast cancer research and treatment - 1 May 2008
Langsenlehner Uwe, Wolf Gerald, Langsenlehner Tanja, Gerger Armin, Hofmann Günter, Clar Heimo, Wascher Thomas C, Paulweber Bernhard, Samonigg Hellmut, Krippl Peter, Renner Wilfried
Abstract excerpt
PURPOSE: Vascular endothelial growth factor (VEGF) is a key regulator of tumor-induced angiogenesis and is required for growth of tumors. We tested the hypothesis that VEGF gene polymorphisms may be associated with breast cancer. EXPERIMENTAL DESIGN: We performed a case-control study including 80...
Topics
- Austria
- Breast Neoplasms
- Case-Control Studies
- Environmental Exposure
- Female
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Incidence
- Linkage Disequilibrium
- Male
- Middle Aged
- Polymerase Chain Reaction