Article
Polymorphisms in angiogenesis-related genes and prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2008
Jacobs Eric J, Hsing Ann W, Bain Elizabeth B, Stevens Victoria L, Wang Yiting, Chen Jinbo, Chanock Stephen J, Zheng S Lilly, Xu Jianfeng, Thun Michael J, Calle Eugenia E, Rodriguez Carmen
Abstract excerpt
BACKGROUND: Angiogenesis is required for development and progression of prostate cancer. Potentially functional single nucleotide polymorphisms (SNP) in genes important in prostate angiogenesis (VEGF, HIF1A, and NOS3) have previously been associated with risk or severity of prostate cancer. METHODS: Prostate cancer cases (n = 1,425) and controls (n = 1,453) were selected from the Cancer Prevention Study II...
Topics
- Aged
- Case-Control Studies
- Confidence Intervals
- Humans
- Logistic Models
- Male
- Middle Aged
- Neovascularization, Pathologic
- Polymorphism, Genetic
- Polymorphism, Single Nucleotide
- Prostatic Neoplasms