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Article

Pharmacogenetic pathway analysis of docetaxel elimination.

Clinical pharmacology and therapeutics - 1 Feb 2009

Baker S D, Verweij J, Cusatis G A, van Schaik R H, Marsh S, Orwick S J, Franke R M, Hu S, Schuetz E G, Lamba V, Messersmith W A, Wolff A C, Carducci M A, Sparreboom A

Abstract excerpt

The purpose of this study was to evaluate the affinity of docetaxel for 14 transporter proteins and assess the functional significance of 17 variants in five genes involved in drug elimination. Among the transfected models investigated, OATP1B3 (SLCO1B3) was identified as the most efficient influ...

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Share to Cytochrome P-450 CYP3A
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 18509327
DOI: 10.1038/clpt.2008.95
PMCID: PMC4612590

Genes

ABCB1
ABCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18509327-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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