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Article

Activation of hepatocytes by extracellular heat shock protein 72.

American journal of physiology. Cell physiology - 1 Aug 2008

Galloway Elizabeth, Shin Thomas, Huber Nadine, Eismann Thorsten, Kuboki Satoshi, Schuster Rebecca, Blanchard John, Wong Hector R, Lentsch Alex B

Abstract excerpt

Heat shock protein (HSP) 72 is released by cells during stress and injury. HSP-72 also stimulates the release of cytokines in macrophages by binding to Toll-like receptors (TLR) 2 and 4. Circulating levels of HSP-72 increase during hepatic ischemia-reperfusion injury. The role of extracellular HS...

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Share to Hepatocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18508912
DOI: 10.1152/ajpcell.00032.2008
PMCID: PMC2518414

Genes

MIP
TLR2
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18508912-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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