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Article

Major role of HSP70 as a paracrine inducer of cytokine production in human oxidized LDL treated macrophages.

Atherosclerosis - 1 Mar 2006

Svensson Per-Arne, Asea Alexzander, Englund Mikael C O, Bausero Maria A, Jernås Margareta, Wiklund Olov, Ohlsson Bertil G, Carlsson Lena M S, Carlsson Björn

Abstract excerpt

Lipid accumulation and inflammation are key hallmarks of the atherosclerotic plaque and macrophage uptake of oxidized low-density lipoprotein (oxLDL) is believed to drive these processes. Initial experiments show that supernatants from oxLDL treated macrophages could induce IL-1beta production in naïve macrophages. To search for potential paracrine mediators that could mediate this effect a DNA microarray scan of...

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Share to Enzyme-Linked Immunosorbent Assay
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15993884
DOI: 10.1016/j.atherosclerosis.2005.05.007
PMCID: PMC1762098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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