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Article

Alternative mechanism by which IFN-gamma enhances tumor recognition: active release of heat shock protein 72.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2005

Bausero Maria A, Gastpar Robert, Multhoff Gabriele, Asea Alexzander

Abstract excerpt

IFN-gamma exhibits differential effects depending on the target and can induce cellular activation and enhance survival or mediate cell death via activation of apoptotic pathways. In this study, we demonstrate an alternative mechanism by which IFN-gamma enhances tumor recognition, mediated by the active release of Hsp72. We demonstrate that stimulation of 4T1 breast adenocarcinoma cells and K562 erythroleukemic...

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Identifiers

PMID: 16116176
DOI: 10.4049/jimmunol.175.5.2900
PMCID: PMC1762097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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