Article
Exact trait-model-free tests for linkage detection in pedigrees.
Annals of human genetics - 1 Sept 2008
Basu S, Di Y, Thompson E A
Abstract excerpt
A number of trait-model-free tests have been proposed for linkage detection between a genomic region and a trait. These tests involve testing the dependence in segregation between a trait and marker alleles by assigning a score to every possible identity-by-descent configuration of the pedigree members without modeling the trait, and then averaging the scores over all such configurations compatible with the...
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