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Article

Computationally efficient multipoint linkage analysis on extended pedigrees for trait models with two contributing major Loci.

Genetic epidemiology - 1 Sept 2012

Su Ming, Thompson Elizabeth A

Abstract excerpt

We have developed a computationally efficient method for multipoint linkage analysis on extended pedigrees for trait models having a two-locus quantitative trait loci (QTL) effect. The method has been implemented in the program, hg_lod, which uses the Markov chain Monte Carlo (MCMC) method to sample realizations of descent patterns conditional on marker data, then calculates the trait likelihood for each...

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Identifiers

PMID: 22740194
DOI: 10.1002/gepi.21653
PMCID: PMC3868922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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