Article
Acquired uniparental disomy in myeloproliferative neoplasms.
Hematology/oncology clinics of North America - 1 Oct 2012
Score Joannah, Cross Nicholas C P
Abstract excerpt
The finding of somatically acquired uniparental disomy, where both copies of a chromosome pair or parts of chromosomes have originated from one parent, has led to the discovery of several novel mutated genes in myeloproliferative neoplasms and related disorders. This article examines how the development of single nucleotide polymorphism array technology has facilitated the identification of regions of acquired...
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