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Article

Acquired uniparental disomy of chromosome 9p in hematologic malignancies.

Experimental hematology - 1 Aug 2016

Wang Linghua, Wheeler David A, Prchal Josef T

Abstract excerpt

Acquired uniparental disomy (aUPD) is a common and recurrent molecular event in human cancers that leads to homozygosity for tumor suppressor genes as well as oncogenes, while retaining the diploid chromosomal complement. Because of the lack of copy number change, aUPD is undetectable by comparative genome hybridization, so the magnitude of this genetic change was underappreciated in the past. 9p aUPD was first...

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Source

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Identifiers

PMID: 26646991
DOI: 10.1016/j.exphem.2015.11.005
PMCID: PMC5268131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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