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Article

Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study.

Experimental gerontology - 1 Aug 2008

Trompet S, de Craen A J M, Slagboom P, Shepherd J, Blauw G J, Murphy M B, Bollen E L E M, Buckley B M, Ford I, Gaw A, Macfarlane P W, Packard C J, Stott D J, Westendorp R G J, Jukema J W

Abstract excerpt

Inflammation plays a prominent role in the development of atherosclerosis, which is the most important risk factor for vascular events. Lymphotoxin-alpha (LTA) is a pro-inflammatory cytokine and is found to be expressed in atherosclerotic lesions. We investigated the association between the C804A polymorphism within the LTA gene and coronary and cerebrovascular events in 5804 participants of the PROspective Study...

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Source

Identifiers

PMID: 18504081
DOI: 10.1016/j.exger.2008.04.006

Genes

LTA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study.PMID 18504081Read ↗

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