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Article

Association between PPARγ polymorphisms and neurological functional disability of ischemic stroke.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Feb 2025

Yan Ran, Qiu Xin, Dai Yalun, Jiang Yingyu, Gu Hongqiu, Jiang Yong, Ding Lingling, Cheng Si, Meng Xia, Wang Yilong, Zhao Xingquan, Li Hao, Wang Yongjun, Li Zixiao

Abstract excerpt

Peroxisome proliferator-activated receptor-γ (PPARγ) plays a protective role against brain injury after stroke in mice. However, the relationship between PPARγ gene polymorphisms and the functional outcome of acute ischemic stroke (AIS) remains unknown. 8822 patients from The Third China National Stroke Registry (CNSR-III) after whole-genome sequencing, two functional single nucleotide polymorphisms(SNPs) in...

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PMID: 39161254
DOI: 10.1177/0271678X241274681
PMCID: PMC11572223

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