Article
Increased risk of gastric cancer in Japanese subjects is associated with microsatellite polymorphisms in the heme oxygenase-1 and the inducible nitric oxide synthase gene promoters.
Cancer letters - 28 Sept 2008
Sawa Tomohiro, Mounawar Mounia, Tatemichi Masayuki, Gilibert Isabelle, Katoh Takahiko, Ohshima Hiroshi
Abstract excerpt
Microsatellite polymorphism in the promoter region of the heme oxygenase-1 (HO-1) gene was analyzed jointly with that of the inducible nitric oxide synthase (iNOS) gene among Japanese subjects (control and gastric cancer patients). A higher promoter activity genotype of the HO-1 gene was associated with increased risk for gastric cancer in women. Gastric cancer risk was notably increased in subjects carrying a...
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