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Article

Interleukin-8 promoter polymorphism increases the risk of atrophic gastritis and gastric cancer in Japan.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2005

Taguchi Ayumu, Ohmiya Naoki, Shirai Kennosuke, Mabuchi Nobuyuki, Itoh Akihiro, Hirooka Yoshiki, Niwa Yasumasa, Goto Hidemi

Abstract excerpt

Host genetic susceptibility may influence gastric carcinogenesis caused by Helicobacter pylori infection. We aimed to clarify the relationship of interleukin (IL)-8 polymorphism with the risk of atrophic gastritis and gastric cancer. We examined IL-8 -251 T > A, IL-1B -511 C > T, and IL-1RN intron 2 polymorphisms in 252 healthy controls, 215 individuals with atrophic gastritis, and 396 patients with gastric...

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PMID: 16284368
DOI: 10.1158/1055-9965.EPI-05-0326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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