Article
Interleukin-1 polymorphisms associated with increased risk of gastric cancer.
Nature - 23 Mar 2000
El-Omar E M, Carrington M, Chow W H, McColl K E, Bream J H, Young H A, Herrera J, Lissowska J, Yuan C C, Rothman N, Lanyon G, Martin M, Fraumeni J F, Rabkin C S
Abstract excerpt
Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric physiological response is influenced by the severity and anatomical distribution of gastritis induced by H. pylori. Thus, individuals with gastritis predominantly localized to the antrum retain normal (or even high) acid...
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