Article
The latent membrane protein 2 gene of Epstein-Barr virus is important for efficient B cell immortalization.
The Journal of general virology - 1 Nov 1996
Brielmeier M, Mautner J, Laux G, Hammerschmidt W
Abstract excerpt
The viral latent membrane proteins 2 (LMP2) of Epstein-Barr virus (EBV) were analysed genetically to evaluate their role in B cell immortalization. LMP2 is transcribed as two differently spliced mRNAs which code for the LMP2A and -B proteins, also called terminal protein-1 and -2. LMP2A and -B ar...
Topics
- B-Lymphocytes
- Cell Transformation, Viral
- DNA, Viral
- Genes, Viral
- Herpesvirus 4, Human
- Humans
- Mutation
- Tumor Cells, Cultured
- Viral Matrix Proteins