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Article

Epigenetic inactivation of SFRP genes in oral squamous cell carcinoma.

International journal of oncology - 1 Jun 2008

Sogabe Yohei, Suzuki Hiromu, Toyota Minoru, Ogi Kazuhiro, Imai Takashi, Nojima Masanori, Sasaki Yasushi, Hiratsuka Hiroyoshi, Tokino Takashi

Abstract excerpt

Although mutations of APC, CTNNB1 (beta-catenin) and AXIN1 are rare in oral squamous cell carcinoma (OSCC), activation of the Wnt signaling pathway is thought to play an important role in oral carcinogenesis. In the present study, we examined the relationship between Wnt signaling and epigenetic...

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Source

Identifiers

PMID: 18497987
DOI: 10.3892/ijo_32_6_1253

Genes

APC
CTNNB1
SFRP1
SFRP2
SFRP5
AXIN1
CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18497987-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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