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Article

A human fatty acid amide hydrolase (FAAH) functional gene variant is associated with lower blood pressure in young males.

American journal of hypertension - 1 Aug 2008

Sarzani Riccardo, Bordicchia Marica, Salvi Fabio, Cola Giovanna, Franchi Eliana, Battistoni Ilaria, Mancinelli Lucia, Giovagnoli Andrea, Dessì-Fulgheri Paolo, Rappelli Alessandro

Abstract excerpt

BACKGROUND: Fatty acid amide hydrolase (FAAH) inhibitors, preventing endocannabinoid (EC) degradation, reduce blood pressure (BP) and heart rate in young male (YM) hypertensive rodents. The functional human FAAH 129T gene variant results in reduced protein level and enzymatic activity but its relationship with BP is unknown. This study investigates the relationship among FAAH P129T alleles and cardiovascular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18497731
DOI: 10.1038/ajh.2008.198

Genes

FAAH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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