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Article

Biomarkers of endocannabinoid system activation in severe obesity.

PloS one - 20 Jan 2010

Sipe Jack C, Scott T Michael, Murray Sarah, Harismendy Olivier, Simon Gabriel M, Cravatt Benjamin F, Waalen Jill

Abstract excerpt

BACKGROUND: Obesity is a worldwide epidemic, and severe obesity is a risk factor for many diseases, including diabetes, heart disease, stroke, and some cancers. Endocannabinoid system (ECS) signaling in the brain and peripheral tissues is activated in obesity and plays a role in the regulation of body weight. The main research question here was whether quantitative measurement of plasma endocannabinoids,...

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Identifiers

PMID: 20098695
DOI: 10.1371/journal.pone.0008792
PMCID: PMC2808340

Genes

FAAH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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