Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic aspects of epitestosterone formation and androgen disposition: influence of polymorphisms in CYP17 and UGT2B enzymes.

Pharmacogenetics and genomics - 1 Jun 2008

Schulze Jenny Jakobsson, Lorentzon Mattias, Ohlsson Claes, Lundmark Jonas, Roh Hyung-Keun, Rane Anders, Ekström Lena

Abstract excerpt

OBJECTIVE: Testosterone is a commonly abused androgen in sports and in the gym culture of the society. Its abuse is conventionally disclosed by urinary assay of the testosterone/epitestosterone (T/E) glucuronide ratio, which should not exceed 4. A noteworthy number of athletes, however, have higher natural ratios than 4, most likely because of decreased excretion of epitestosterone glucuronide. Falsely positive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androgens
Share to Gene Dosage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucuronosyltransferase

Share to Minor Histocompatibility Antigens

Share to Pharmacogenetics

Share to Steroid 17-alpha-Hydroxylase

Share to Testosterone

Source

Identifiers

PMID: 18496127
DOI: 10.1097/FPC.0b013e3282fad38a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic aspects of epitestosterone formation and androgen disposition: influence of polymorphisms in CYP17 and UGT2B enzymes.PMID 18496127Read ↗

Epidemiological investigation of the UGT2B17 polymorphism in doping control urine samples and its correlation to T/E ratios.Semantic proximity Read ↗

Doping test results dependent on genotype of uridine diphospho-glucuronosyl transferase 2B17, the major enzyme for testosterone glucuronidation.Semantic proximity Read ↗

Androgen sulfation in healthy UDP-glucuronosyl transferase 2B17 enzyme-deficient men.Semantic proximity Read ↗

Non-steroidal anti-inflammatory drugs interact with testosterone glucuronidation.Semantic proximity Read ↗

[Testosterone metabolism and doping test results].Semantic proximity Read ↗

A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys.Semantic proximity Read ↗

Testosterone challenge and androgen receptor activity in relation to UGT2B17 genotypes.Semantic proximity Read ↗

UDP-glucuronosyltransferase 2B17 genotyping in Japanese athletes and evaluation of the current sports drug testing for detecting testosterone misuse.Semantic proximity Read ↗

Dose-dependent testosterone sensitivity of the steroidal passport and GC-C-IRMS analysis in relation to the UGT2B17 deletion polymorphism.Semantic proximity Read ↗

Potentially harmful advantage to athletes: a putative connection between UGT2B17 gene deletion polymorphism and renal disorders with prolonged use of anabolic androgenic steroidsSemantic proximity Read ↗

Effectiveness of blood steroidal passport markers for detecting testosterone abuse in Asians.Semantic proximity Read ↗

Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.