Article
Non-steroidal anti-inflammatory drugs interact with testosterone glucuronidation.
Steroids - 1 Nov 2009
Sten Taina, Finel Moshe, Ask Birgitta, Rane Anders, Ekström Lena
Abstract excerpt
Testosterone and epitestosterone are secreted mainly as glucuronide metabolites and the urinary ratio of testosterone glucuronide to epitestosterone glucuronide, often called T/E, serves as a marker for possible anabolic steroids abuse by athletes. UDP-glucuronosyltransferase (UGT) 2B17 is the most important catalyst of testosterone glucuronidation. The T/E might be affected by drugs that interact with UGT2B17,...
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