Article
Arabidopsis DEMETER-LIKE proteins DML2 and DML3 are required for appropriate distribution of DNA methylation marks.
Plant molecular biology - 1 Aug 2008
Ortega-Galisteo Ana Pilar, Morales-Ruiz Teresa, Ariza Rafael R, Roldán-Arjona Teresa
Abstract excerpt
Cytosine DNA methylation is a stable epigenetic mark for maintenance of gene silencing across cellular divisions, but it is a reversible modification. Genetic and biochemical studies have revealed that the Arabidopsis DNA glycosylase domain-containing proteins ROS1 (REPRESSOR OF SILENCING 1) and DME (DEMETER) initiate erasure of 5-methylcytosine through a base excision repair process. The Arabidopsis genome...
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