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Article

A histone acetyltransferase regulates active DNA demethylation in Arabidopsis.

Science (New York, N.Y.) - 15 Jun 2012

Qian Weiqiang, Miki Daisuke, Zhang Heng, Liu Yunhua, Zhang Xi, Tang Kai, Kan Yunchao, La Honggui, Li Xiaojie, Li Shaofang, Zhu Xiaohong, Shi Xiaobing, Zhang Kangling, Pontes Olga, Chen Xuemei, Liu Renyi, Gong Zhizhong, Zhu Jian-Kang

Abstract excerpt

Active DNA demethylation is an important part of epigenetic regulation in plants and animals. How active DNA demethylation is regulated and its relationship with histone modification patterns are unclear. Here, we report the discovery of IDM1, a regulator of DNA demethylation in Arabidopsis. IDM1 is required for preventing DNA hypermethylation of highly homologous multicopy genes and other repetitive sequences...

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Identifiers

PMID: 22700931
DOI: 10.1126/science.1219416
PMCID: PMC3575687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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