Article
Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation.
PloS one - 21 May 2008
Bryk Jarosław, Hardouin Emilie, Pugach Irina, Hughes David, Strotmann Rainer, Stoneking Mark, Myles Sean
Abstract excerpt
Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes. From this approach, lists of hundreds of candidate genomic regions for positive selection have been assembled. These candidate regions are expected to contain variants that contribute to adaptive phenotypes, but few of these regions have been associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.