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Article

Contrasting signals of selection at the EDAR gene in global and Latin American populations.

Journal of genetics - 1 Jan 2026

Briceño Moya Jorge, Díaz Muñoz Alejandro, Manríquez-Soto Germán, Flores-Carrasco Sergio

Abstract excerpt

The EDAR gene is a classic target of positive selection in humans, mainly through the nonsynonymous variant rs3827760 (EDARV370A) associated with ectodermal traits. Using high-resolution data from the 1000 Genomes Project, we combined sliding-window F_ST, BayeScan, and extended haplotype homozygosity (EHH) analyses to examine global and Latin American patterns of differentiation. Globally, a strong signal of...

Read the complete abstract on PubMed

Topics

Humans
Selection, Genetic
Haplotypes
Latin America

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Linkage Disequilibrium

Edar Receptor

Polymorphism, Single Nucleotide

Genetics, Population

Evolution, Molecular

Source

Identifiers

PMID: 42687664

Genes

EDAR
FST

Provenance

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