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Article

Quantitative trait loci for urinary albumin in crosses between C57BL/6J and A/J inbred mice in the presence and absence of Apoe.

Genetics - 1 May 2008

Doorenbos Carolien, Tsaih Shirng-Wern, Sheehan Susan, Ishimori Naoki, Navis Gerjan, Churchill Gary, Dipetrillo Keith, Korstanje Ron

Abstract excerpt

We investigated the effect of apolipoprotein E (Apoe) on albuminuria in the males of two independent F2 intercrosses between C57BL/6J and A/J mice, using wild-type inbred strains in the first cross and B6-Apoe(-/-) animals in the second cross. In the first cross, we identified three quantitative trait loci (QTL): chromosome (Chr) 2 [LOD 3.5, peak at 70 cM, confidence interval (C.I.) 28-88 cM]; Chr 9 (LOD 2.0,...

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Identifiers

PMID: 18493081
DOI: 10.1534/genetics.107.085142
PMCID: PMC2390645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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