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Article

Sequence features of HLA-DRB1 locus define putative basis for gene conversion and point mutations.

BMC genomics - 19 May 2008

von Salomé Jenny, Kukkonen Jyrki P

Abstract excerpt

BACKGROUND: HLA/MHC class II molecules show high degree of polymorphism in the human population. The individual polymorphic motifs have been suggested to be propagated and mixed by transfer of genetic material (recombination, gene conversion) between alleles, but no clear molecular basis for this has been identified as yet. A large number of MHC class II allele sequences is publicly available and could be used to...

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Identifiers

PMID: 18489735
DOI: 10.1186/1471-2164-9-228
PMCID: PMC2408603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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