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Article

BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells.

Blood - 1 Aug 2008

Guarini Anna, Chiaretti Sabina, Tavolaro Simona, Maggio Roberta, Peragine Nadia, Citarella Franca, Ricciardi Maria Rosaria, Santangelo Simona, Marinelli Marilisa, De Propris Maria Stefania, Messina Monica, Mauro Francesca Romana, Del Giudice Ilaria, Foà Robert

Abstract excerpt

Chronic lymphocytic leukemia (CLL) patients exhibit a variable clinical course. To investigate the association between clinicobiologic features and responsiveness of CLL cells to anti-IgM stimulation, we evaluated gene expression changes and modifications in cell-cycle distribution, proliferation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Source

Identifiers

PMID: 18487510
DOI: 10.1182/blood-2007-12-127688

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18487510-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgV H unmutated chronic lymphocytic leukemia (CLL) cells.PMID 18487510Read ↗

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