Article
Penalized estimation of haplotype frequencies.
Bioinformatics (Oxford, England) - 15 Jul 2008
Ayers Kristin L, Lange Kenneth
Abstract excerpt
MOTIVATION: Low haplotype diversity and linkage disequilibrium are the rule in short genomic segments. This fact suggests that parsimony should be enforced in estimation of haplotype frequencies. The current article introduces a diversity penalty that automatically discards potential haplotypes w...
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