Article
Estimating haplotype effects on dichotomous outcome for unphased genotype data using a weighted penalized log-likelihood approach.
Human heredity - 1 Jan 2006
Souverein Olga W, Zwinderman Aeilko H, Tanck Michael W T
Abstract excerpt
OBJECTIVE: To develop a method to estimate haplotype effects on dichotomous outcomes when phase is unknown, that can also estimate reliable effects of rare haplotypes. METHODS: In short, the method uses a logistic regression approach, with weights attached to all possible haplotype combinations o...
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