Article
A fast least-squares algorithm for population inference.
BMC bioinformatics - 23 Jan 2013
Parry R Mitchell, Wang May D
Abstract excerpt
BACKGROUND: Population inference is an important problem in genetics used to remove population stratification in genome-wide association studies and to detect migration patterns or shared ancestry. An individual's genotype can be modeled as a probabilistic function of ancestral population memberships, Q, and the allele frequencies in those populations, P. The parameters, P and Q, of this binomial likelihood model...
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