Low frequency of ras activation in 2-acetylaminofluorene- and 3'-methyl-4-(dimethylamino)azobenzene-induced rat hepatocellular carcinomas.

doi:10.1016/0304-3835(91)90188-n

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Article

Low frequency of ras activation in 2-acetylaminofluorene- and 3'-methyl-4-(dimethylamino)azobenzene-induced rat hepatocellular carcinomas.

Cancer letters - 1 Jan 1991

Li H, Lee G H, Liu J, Nomura K, Ohtake K, Kitagawa T

Abstract excerpt

Activation of ras protooncogenes in 11 2-acetylaminofluorene (AAF)-induced hepatocellular carcinomas (HCCs) or liver cell lines and 9 3'-methyl-(dimethylamino)azobenzene (3'-Me-DAB)-induced HCCs in rats was examined using the NIH3T3 cell transfection assay and oligonucleotide hybridization analys...

Topics

2-Acetylaminofluorene
Animals
Blotting, Southern
Carcinoma, Hepatocellular
Cell Transformation, Neoplastic
DNA
Gene Expression Regulation
Genes, ras
Liver Neoplasms
Male
Methyldimethylaminoazobenzene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nucleic Acid Hybridization

Polymerase Chain Reaction

Rats

Repetitive Sequences, Nucleic Acid

Transfection

Source

Open in PubMed

Identifiers

PMID: 1848477
DOI: 10.1016/0304-3835(91)90188-n

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1848477-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Low frequency of ras activation in 2-acetylaminofluorene- and 3'-methyl-4-(dimethylamino)azobenzene-induced rat hepatocellular carcinomas.PMID 1848477Read ↗

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