Molecular mechanisms for the regulation of aryl sulfotransferase IV expression during 2-acetylaminofluorene-induced hepatocarcinogenesis in rat.

doi:10.1016/0009-2797(94)90075-2

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Article

Molecular mechanisms for the regulation of aryl sulfotransferase IV expression during 2-acetylaminofluorene-induced hepatocarcinogenesis in rat.

Chemico-biological interactions - 1 Jun 1994

Ringer D P, Yerokun T, Khan A S

Abstract excerpt

The dietary administration of 2-acetylaminofluorene to male rats to induce hepatocarcinogenesis causes a reversible as well as persistent down-modulation of N-hydroxy-2AAF sulfotransferase activity. Studies are presented which indicate that several molecular mechanisms may be involved in the down...

Topics

2-Acetylaminofluorene
Animals
Down-Regulation
Female
Gene Expression Regulation, Enzymologic
Hormones
Liver
Liver Neoplasms, Experimental
Male
Mutation
RNA, Messenger
Rats
Sulfotransferases

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