Article
Prostate cancer risk associated loci in African Americans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2009
Xu Jianfeng, Kibel Adam S, Hu Jennifer J, Turner Aubrey R, Pruett Kristen, Zheng Siqun Lilly, Sun Jielin, Isaacs Sarah D, Wiley Kathleen E, Kim Seong-Tae, Hsu Fang-Chi, Wu William, Torti Frank M, Walsh Patrick C, Chang Bao-Li, Isaacs William B
Abstract excerpt
Four genome-wide association studies, all in populations of European descent, have identified 20 independent single nucleotide polymorphisms (SNP) in 20 regions that are associated with prostate cancer risk. We evaluated these 20 SNPs in a combined African American (AA) study, with 868 prostate cancer patients and 878 control subjects. For 17 of these 20 SNPs, implicated risk-associated alleles were found to be...
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