Article
Microsomal triglyceride transfer protein (MTP) -493G/T gene polymorphism contributes to fat liver accumulation in HCV genotype 3 infected patients.
Journal of viral hepatitis - 1 Oct 2008
Zampino R, Ingrosso D, Durante-Mangoni E, Capasso R, Tripodi M-F, Restivo L, Zappia V, Ruggiero G, Adinolfi L E
Abstract excerpt
SUMMARY: (A) A reduced activity of microsomal triglyceride transfer protein (MTP), a key enzyme of assembly/secretion of lipoproteins, is related to HCV steatosis. Host genetic background may influence development of steatosis. The aim of the study was to investigate the association between MTP-493 G/T gene polymorphism, fat liver accumulation and fibrosis progression in HCV infected patients. A total of 102...
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