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Article

Microsomal triglyceride transfer protein polymorphism (-493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C.

Liver international : official journal of the International Association for the Study of the Liver - 1 Apr 2009

Mirandola Silvia, Osterreicher Christoph H, Marcolongo Moira, Datz Christian, Aigner Elmar, Schlabrakowski Anne, Realdon Stefano, Gerotto Martina, Alberti Alfredo, Stickel Felix

Abstract excerpt

BACKGROUND: Hepatic steatosis may promote progression of chronic hepatitis C (CHC). Microsomal triglyceride transfer protein (MTP) is required for assembly and secretion of ApoB lipoprotein and is implicated in hepatitis C virus (HCV)-related steatosis. The MTP -493G/T polymorphism may promote li...

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Source

Identifiers

PMID: 19018985
DOI: 10.1111/j.1478-3231.2008.01892.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19018985-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Microsomal triglyceride transfer protein polymorphism (-493G/T) is associated with hepatic steatosis in patients with chronic hepatitis C.PMID 19018985Read ↗

Genetic variation in the microsomal triglyceride transfer protein (-493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus.Semantic proximity Read ↗

Microsomal triglyceride transfer protein (MTP) -493G/T gene polymorphism contributes to fat liver accumulation in HCV genotype 3 infected patients.Semantic proximity Read ↗

MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients.Semantic proximity Read ↗

Association between MTTP genotype (-493G/T) polymorphism and hepatic steatosis in hepatitis C: a systematic review and meta-analysis.Semantic proximity Read ↗

Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis.Semantic proximity Read ↗

A polymorphism in the microsomal triglyceride transfer protein can predict the response to antiviral therapy in Egyptian patients with chronic hepatitis C virus genotype 4 infection.Semantic proximity Read ↗

Effect of MTTP -493G/T, I128T, Q95H and Q244E polymorphisms on hepatic steatosis in patients with chronic hepatitis.Semantic proximity Read ↗

MTP -493G>T polymorphism and susceptibility to nonalcoholic fatty liver disease: a meta-analysis.Semantic proximity Read ↗

Genotype 3 Infection: The Last Stand of Hepatitis C Virus.Semantic proximity Read ↗

PNPLA3 rs738409 causes steatosis according to viral & IL28B genotypes in hepatitis C.Semantic proximity Read ↗

Correlation between MTP -493G>T polymorphism and non-alcoholic fatty liver disease risk: a meta-analysis.Semantic proximity Read ↗

Hepatic steatosis in chronic hepatitis C: baseline host and viral characteristics and influence on response to therapy with peginterferon alpha-2a plus ribavirin.Semantic proximity Read ↗

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