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Article

Genetic variation in the microsomal triglyceride transfer protein (-493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus.

BMC infectious diseases - 29 Mar 2017

Magri Mariana Cavalheiro, Prata Thamiris Vaz Gago, Manchiero Caroline, Dantas Bianca Peixoto, Mazza Celso Carmo, Tengan Fátima Mitiko

Abstract excerpt

BACKGROUND: In chronic hepatitis C, the fibrosis progression rates are extremely variable and can be influenced by factors associated with the host, virus and environment. Among the associated metabolic factors, hepatic steatosis is characterized by an accumulation of triglycerides in hepatocytes. In the host, genetic determinants of hepatic steatosis are observed, such as single-nucleotide polymorphisms (SNPs)...

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Identifiers

PMID: 28356060
DOI: 10.1186/s12879-017-2340-x
PMCID: PMC5372317

Genes

MTTP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in the microsomal triglyceride transfer protein (-493G/T) is associated with hepatic steatosis in patients infected with hepatitis C virus.PMID 28356060Read ↗

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