Article
Association analysis of IL20RA and IL20RB genes in psoriasis.
Genes and immunity - 1 Jul 2008
Kingo K, Mössner R, Rätsep R, Raud K, Krüger U, Silm H, Vasar E, Reich K, Kõks S
Abstract excerpt
The interleukin-20-receptor I complex (IL-20-RI) is composed of two chains, IL20RA and IL20RB. Its ligands are the three members of the IL19 subfamily of cytokines, IL-19, IL-20 and IL-24. These cytokines are important in the manifestation of psoriatic lesions and, recently, an association of polymorphisms of IL20 with psoriasis has been described. In the present study we tested the hypotheses that genetic...
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